Intraoperative Neurophysiology (IOM) in Neurosurgery

Staff

• PhD Jonathan Wermelinger (Postdoc, Mathematician)

• MD Pablo Abel Alvarez Abut (MD, Neurophysiologist)

• M. Sc. Qendresa Parduzi (PhD Student, Neuroscientist)

• Anne Leyh (Technician)

• Christin Kauert (Technician)

• Christina Weirich-Pfaff (Technician)

• Several medical students (Master and Doctorate)

Research focuses

• Intraoperative neuromonitoring and mapping for gliomas in eloquent areas; continuous dynamic mapping; awake operations; cortico-cortical evoked potentials

• Functional monitoring including reflex studies during skull base tumors and tumors of the brain stem

• Monitoring of spinal cord tumors and development of new mapping paradigms

• Pre- and postoperative analysis of the motor system using navigated TMS

• Machine learning approaches to improve intraoperative warning criteria

Fundings

• SITEM Insel Support Funds

• ID-Grant and CTU Grants

• Inomed and Zeiss Industrial Intraoperative Neurophysiology Project Contribution

• European Association of Neurosurgery (EANS) grants

• Deutsche Gesellschaft of Neurosurgery (DGNC) Grants

• Schweizer Akademie für Medizinische Wissenschaften (SAMW)

Short description

The IOM research group of the department of neurosurgery focus on functional guidance during neurosurgical interventions to improve patient safety during high-risk surgeries. Therefore, we investigate neurophysiological mapping techniques, evoked potentials and reflex studies as well as machine learning approaches. This involves intraoperative neurophysiology and perioperative navigated transcranial magnetic stimulation.